ADA 2026: The Multi-Agonist and Oral Incretin Readouts, Summarized
ADA 2026 delivered phase 3 data on a triple GLP-1/GIP/glucagon agonist, a dual agonist, CagriSema and two oral agents. Here is the map.
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ADA 2026 delivered phase 3 data on a triple GLP-1/GIP/glucagon agonist, a dual agonist, CagriSema and two oral agents. Here is the map.
In 2026 FDA moved to end bulk compounding of GLP-1 drugs and began citing research-labeled sellers of the same peptides. The two stories are one story.
How a single peptide came to activate three proglucagon-family receptors, what phase 2 trials of the class reported, and what is still unknown.
The biology behind GLP-1: where it comes from, what it does, why the native hormone lasts two minutes, and how synthetic analogues were built to last a week.
Three related receptors, three different jobs. How the biology of GLP-1, GIP and glucagon receptors led from selective agonists to dual and triple agonists.
What the SUSTAIN, STEP, SURPASS and SURMOUNT programs show about a GLP-1 agonist and a GLP-1/GIP dual agonist, and what the comparison does and does not settle.
A map of the peptide classes studied for neuroprotection, melanocortin fragments, incretins, neurotrophin mimetics, mitochondrial peptides, and how each fared.
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