What Is NAD+? Cellular Energy, Sirtuins and the Research Record
A plain-language guide to NAD+: what it does in redox metabolism and signaling, why it declines with age, and what human and animal studies have shown.
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mitochondria
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Mitochondrial-Derived Peptides: MOTS-c, Humanin and SHLPs
An overview of the peptides encoded in mitochondrial DNA, humanin, the SHLP family and MOTS-c, and what two decades of research have shown about them.
Neuroprotective Peptides: An Overview of the Research Landscape
A map of the peptide classes studied for neuroprotection, melanocortin fragments, incretins, neurotrophin mimetics, mitochondrial peptides, and how each fared.
SS-31 (Elamipretide): Mitochondrial Membrane Research Overview
How the cardiolipin-binding peptide SS-31 went from a Cornell lab to an FDA-approved drug for Barth syndrome, and what the failed trials along the way showed.
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